QuoCo

The tool developped to help clinicians follow the cognition of their elderly patients, using morphometric measurements of pediatric growth charts.

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About QuoCo

Context

Is has been repeatedly shown that an individual's cognition diminishes as its age increases. However, what is considered as a normal cognitive decline? How can one distinguish the onset of a neurological disease solely from the impact of age?

We proudly introduce QuoCo, the newly developed tool built to help the clinician answer these questions in a simple and effective way using percentile curves.

Where do the curves come from?

Developed by our interdisciplinary team of researchers, QuoCo was built on over 8,000 entries from the well-known "Canadian Study of Health and Aging" (CSHA). The Cognitive Curves (CC) were generated, then validated using the National Alzheimer’s Coordinating Center' UDS database.

What will you need to use QuoCo?

You will only need the age, the number of years of education and the patient's score to the MMSE (ideally with WORLD spelled backwards). By positioning the patient's cognitive performance on the Cognitive Curves (CC), you will be able to assess its current cognitive state or cognitive trajectory. Ideally, you should set the MMSE baseline when the patient is aroung 65-70 years of age and clearly intact on the cognitive level.

Calculations

You will only need to calculate the patient's QuoCo and its Standardized age (SA) and place those results on the Cognitive Curves.

You should note that the patient's age must be at least 65 years old and that education values higher that 14 years are capped at 14 during the computations.

The age and the education are always represented in years.

Results interpretation

If a result on the Cognitive Curves (CC) is within the cutoff grayed zone, the patient's cognitive state is probably abnormal and will be considered as suspect. If the trajectory between the baseline and the most recent test result drops by more than one percentile (one colored line), the patient's cognitive trajectory is probably abnormal and will be considered as suspect.

Here's an example of an elderly woman with 12 years old education :

At 89 years of age, she obtained 26 out of 30 on MMSE.

By placing her result on the CC, we obtain :


At 68 years of age, she obtained 30 out of 30 on MMSE.

We can now see her cognitive trajectory over time :


This case shows an abnormal cognitive decline as the QuoCo drops by more than one interval.

Cognitive trajectory examples




Have any questions? Visit our Frequently asked questions section for more answers,

or watch our tutorial to learn in detail how to use the cognitive curves.

Using QuoCo

Download the PDF version of the cognitive chart,
or download the QuoCo mobile app now available on iPhone and iPad.

The team behind QuoCo

Patrick Bernier

MD/PhD/CCMF

Conceptor and co-developer of the tool
Project manager

Christian Gourdeau

MSc ing physique

Co-developer of the tool
Leader of the calculations, analysis and modeling

Robert Laforce Jr

MD/PhD/FRCP

Head of research and publication

Pierre-Hugues Carmichael

 

Biostatistician and responsible for the validation

Jean-Pierre Beauchemin

MD

Clinical and scientific advisor

Marc-Antoine Fortier

 

Developer of the mobile application
Designer of the website

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