Is has been repeatedly shown that an individual's cognition diminishes as its age increases. However, what is considered as a normal cognitive decline? How can one distinguish the onset of a neurological disease solely from the impact of age?
We proudly introduce QuoCo, the newly developed tool built to help the clinician answer these questions in a simple and effective way using percentile curves.
Developed by our interdisciplinary team of researchers, QuoCo was built on over 8,000 entries from the well-known "Canadian Study of Health and Aging" (CSHA). The Cognitive Curves (CC) were generated, then validated using the National Alzheimer’s Coordinating Center' UDS database.
You will only need the age, the number of years of education and the patient's score to the MMSE (ideally with WORLD spelled backwards). By positioning the patient's cognitive performance on the Cognitive Curves (CC), you will be able to assess its current cognitive state or cognitive trajectory. Ideally, you should set the MMSE baseline when the patient is aroung 65-70 years of age and clearly intact on the cognitive level.
You will only need to calculate the patient's QuoCo and its Standardized age (SA) and place those results on the Cognitive Curves.
You should note that the patient's age must be at least 65 years old and that education values higher that 14 years are capped at 14 during the computations.
The age and the education are always represented in years.
If a result on the Cognitive Curves (CC) is within the cutoff grayed zone, the patient's cognitive state is probably abnormal and will be considered as suspect. If the trajectory between the baseline and the most recent test result drops by more than one percentile (one colored line), the patient's cognitive trajectory is probably abnormal and will be considered as suspect.
Here's an example of an elderly woman with 12 years old education :
At 89 years of age, she obtained 26 out of 30 on MMSE.
At 68 years of age, she obtained 30 out of 30 on MMSE.
This case shows an abnormal cognitive decline as the QuoCo drops by more than one interval.
Download the PDF version of the cognitive chart, or download the QuoCo mobile app now available on iPhone and iPad.